ABSTRACT
To determine the importance of careful history along with multi-modal clinical neurophysiology [CNP] procedures in diagnosis of rare neurologic disorders landau kleffener sundrome. All patients who referred to CNP lab between the age 2-10 years for brainstem auditory evoked potential [BAEP] as a part of evaluation of aphasia were interviewed [Group A] Those had history of seizures in addition to the primary symptom underwent a complementary EEG in addition to BAEP Similarly all the patients referred to CNP lab between the age 2-10 years for EEG as a part of evaluation of seizures were interviewed [Group B]. Those who had history of aphasia in addition to the seizures underwent complementary BAEP in addition to BEG. The patient who had normal BAEP and abnormal EEG from both the groups were then followed up. They were seen by pediatric neurologist and had a MRI brain to exclude structural lesions. Total of 40 patients were included in the study. Out of them 31 were male and 9 were female. They were divided into Group A and Group B and were studied. EEG showed focal left temporal epileptiform activity which at times noted in generalized manner with normal BERA. LKS is a rare disorder but it is important to recognize as commonly used antiepileptic medications worsen the seizures associated with this syndrome. Its prognosis is also different from other seizure disorders including temporal lobe epilepsy. Vigilant observation towards CNP procedures, history and neurological examination will help physician in diagnosing syndromes like landau Kleffner